Wednesday, December 16, 2020

Phage Hunt Anyone?

Phage Hunting Expectition, Anyone?

Why isn't there probiotic toothpaste or FnpΦ02 (the phage in the Siphoviridae family to fight off  Fusobacterium nucleatum, one of the bacterium that causes bad breath and more damaging: gingivitis, periodontal disease, etc.). A phage for bad breath and gingivitis could be revolutionary, rather than killing off all the oral bacteria, just target the main offenders. These are the questions that popped up after reading this recent Dec 2020 New Yorker article on phages becoming the way to go now that antibiotics are not working and creating more virulent strains of bacteria. 

I suggested to a friend that we should hit the sewer pipes and septic tanks on an adventurous phage hunt, and set up cultivation stations, to ramp up supply. But, of course, insurance companies aren't paying for phage therapy that I know of. 

Can you imagine the beginning of such a story comes to mind: 

Two men, on a phage hunt, pry open the doors of septic tanks, lower in the vials, and bring them up to cork some of the most vile sewage known (and ironically created by) man, in order to transform this into medicine - what a break through right?! 

Who's coming with us?!



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